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The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei

The endoplasmic reticulum membrane complex (EMC) is a versatile complex that plays a key role in membrane protein biogenesis in the ER. Deletion of the complex has wide-ranging consequences including ER stress, disturbance in lipid transport and organelle tethering, among others. Here we report the...

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Detalles Bibliográficos
Autores principales: Iyer, Advaitha, Niemann, Moritz, Serricchio, Mauro, Dewar, Caroline E., Oeljeklaus, Silke, Farine, Luce, Warscheid, Bettina, Schneider, André, Bütikofer, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113592/
https://www.ncbi.nlm.nih.gov/pubmed/35500022
http://dx.doi.org/10.1371/journal.ppat.1009717