Assessing in vivo mutation frequencies and creating a high-resolution genome-wide map of fitness costs of Hepatitis C virus

Like many viruses, Hepatitis C Virus (HCV) has a high mutation rate, which helps the virus adapt quickly, but mutations come with fitness costs. Fitness costs can be studied by different approaches, such as experimental or frequency-based approaches. The frequency-based approach is particularly usef...

Descripción completa

Detalles Bibliográficos
Autores principales: Tisthammer, Kaho H., Solis, Caroline, Orcales, Faye, Nzerem, Madu, Winstead, Ryan, Dong, Weiyan, Joy, Jeffrey B., Pennings, Pleuni S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113599/
https://www.ncbi.nlm.nih.gov/pubmed/35500034
http://dx.doi.org/10.1371/journal.pgen.1010179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113599/
https://www.ncbi.nlm.nih.gov/pubmed/35500034
http://dx.doi.org/10.1371/journal.pgen.1010179

Ejemplares similares