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Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection

The ability to treat severe viral infections is limited by our understanding of the mechanisms behind virus-induced immunopathology. While the role of type I interferons (IFNs) in early control of viral replication is clear, less is known about how IFNs can regulate the development of immunopatholog...

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Detalles Bibliográficos
Autores principales: Lee, Amanda J., Feng, Emily, Chew, Marianne V., Balint, Elizabeth, Poznanski, Sophie M., Giles, Elizabeth, Zhang, Ali, Marzok, Art, Revill, Spencer D., Vahedi, Fatemeh, Dubey, Anisha, Ayaub, Ehab, Jimenez-Saiz, Rodrigo, McGrath, Joshua J. C., Ritchie, Tyrah M., Jordana, Manel, Jonigk, Danny D., Ackermann, Maximilian, Ask, Kjetil, Miller, Matthew, Richards, Carl D., Ashkar, Ali A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113601/
https://www.ncbi.nlm.nih.gov/pubmed/35512020
http://dx.doi.org/10.1371/journal.ppat.1010471