TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells

It remains unclear how the pro-immunogenic maturation of conventional dendritic cells (cDCs) abrogates their tolerogenic functions. Here, we report that the loss of tolerogenic functions depends on the rapid death of BTLA(hi) cDC1s, which, in the steady state, are present in systemic peripheral lymp...

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Detalles Bibliográficos
Autores principales: Iberg, Courtney A., Bourque, Jessica, Fallahee, Ian, Son, Sungho, Hawiger, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113652/
https://www.ncbi.nlm.nih.gov/pubmed/35417681
http://dx.doi.org/10.1016/j.celrep.2022.110657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113652/
https://www.ncbi.nlm.nih.gov/pubmed/35417681
http://dx.doi.org/10.1016/j.celrep.2022.110657

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