Cargando…
TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells
It remains unclear how the pro-immunogenic maturation of conventional dendritic cells (cDCs) abrogates their tolerogenic functions. Here, we report that the loss of tolerogenic functions depends on the rapid death of BTLA(hi) cDC1s, which, in the steady state, are present in systemic peripheral lymp...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113652/ https://www.ncbi.nlm.nih.gov/pubmed/35417681 http://dx.doi.org/10.1016/j.celrep.2022.110657 |