Design, immunogenicity, and efficacy of a pan-sarbecovirus dendritic-cell targeting vaccine

BACKGROUND: There is an urgent need of a new generation of vaccine that are able to enhance protection against SARS-CoV-2 and related variants of concern (VOC) and emerging coronaviruses. METHODS: We identified conserved T- and B-cell epitopes from Spike (S) and Nucleocapsid (N) highly homologous to...

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Detalles Bibliográficos
Autores principales: Coléon, Séverin, Wiedemann, Aurélie, Surénaud, Mathieu, Lacabaratz, Christine, Hue, Sophie, Prague, Mélanie, Cervantes-Gonzalez, Minerva, Wang, Zhiqing, Ellis, Jerome, Sansoni, Amandine, Pierini, Camille, Bardin, Quentin, Fabregue, Manon, Sharkaoui, Sarah, Hoest, Philippe, Dupaty, Léa, Picard, Florence, El Hajj, Marwa, Centlivre, Mireille, Ghosn, Jade, Thiébaut, Rodolphe, Cardinaud, Sylvain, Malissen, Bernard, Zurawski, Gérard, Zarubica, Ana, Zurawski, Sandra M., Godot, Véronique, Lévy, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113741/
https://www.ncbi.nlm.nih.gov/pubmed/35594660
http://dx.doi.org/10.1016/j.ebiom.2022.104062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113741/
https://www.ncbi.nlm.nih.gov/pubmed/35594660
http://dx.doi.org/10.1016/j.ebiom.2022.104062

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