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Intermediate hypocretin-1 cerebrospinal fluid levels and typical cataplexy: their significance in the diagnosis of narcolepsy type 1

STUDY OBJECTIVES: The diagnosis of narcolepsy type 1 (NT1) is based upon the presence of cataplexy and/or a cerebrospinal fluid (CSF) hypocretin-1/orexin-A level ≤ 110 pg/mL. We determined the clinical and diagnostic characteristics of patients with intermediate hypocretin-1 levels (111–200 pg/mL) a...

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Detalles Bibliográficos
Autores principales: van der Hoeven, Adrienne Elisabeth, Fronczek, Rolf, Schinkelshoek, Mink Sebastian, Roelandse, Frederik Willem Cornelis, Bakker, Jaap Adriaan, Overeem, Sebastiaan, Bijlenga, Denise, Lammers, Gert Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113791/
https://www.ncbi.nlm.nih.gov/pubmed/35554594
http://dx.doi.org/10.1093/sleep/zsac052