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Acetaminophen (APAP, Paracetamol) Interferes With the First Trimester Human Fetal Ovary Development in an Ex Vivo Model

CONTEXT: Acetaminophen (APAP, paracetamol) is widely used by pregnant women. Although long considered safe, growing evidence indicates that APAP is an endocrine disruptor since in utero exposure may be associated with a higher risk of male genital tract abnormalities. In rodents, fetal exposure has...

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Detalles Bibliográficos
Autores principales: Lecante, Laetitia L, Leverrier-Penna, Sabrina, Gicquel, Thomas, Giton, Frank, Costet, Nathalie, Desdoits-Lethimonier, Christèle, Lesné, Laurianne, Fromenty, Bernard, Lavoué, Vincent, Rolland, Antoine D, Mazaud-Guittot, Séverine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113793/
https://www.ncbi.nlm.nih.gov/pubmed/35147701
http://dx.doi.org/10.1210/clinem/dgac080