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A mesenchymal to epithelial switch in Fgf10 expression specifies an evolutionary-conserved population of ionocytes in salivary glands

Fibroblast growth factor 10 (FGF10) is well established as a mesenchyme-derived growth factor and a critical regulator of fetal organ development in mice and humans. Using a single-cell RNA sequencing (RNA-seq) atlas of salivary gland (SG) and a tamoxifen inducible Fgf10(CreERT2):R26-tdTomato mouse,...

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Detalles Bibliográficos
Autores principales: Mauduit, Olivier, Aure, Marit H., Delcroix, Vanessa, Basova, Liana, Srivastava, Amrita, Umazume, Takeshi, Mays, Jacqueline W., Bellusci, Saverio, Tucker, Abigail S., Hajihosseini, Mohammad K., Hoffman, Matthew P., Makarenkova, Helen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113928/
https://www.ncbi.nlm.nih.gov/pubmed/35417692
http://dx.doi.org/10.1016/j.celrep.2022.110663