Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory

Throughout the genome, nucleosomes often form regular arrays that differ in nucleosome repeat length (NRL), occupancy of linker histone H1 and transcriptional activity. Here, we report cryo-EM structures of human H1-containing tetranucleosome arrays with four physiologically relevant NRLs. The struc...

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Detalles Bibliográficos
Autores principales: Dombrowski, Marco, Engeholm, Maik, Dienemann, Christian, Dodonova, Svetlana, Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113941/
https://www.ncbi.nlm.nih.gov/pubmed/35581345
http://dx.doi.org/10.1038/s41594-022-00768-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113941/
https://www.ncbi.nlm.nih.gov/pubmed/35581345
http://dx.doi.org/10.1038/s41594-022-00768-w

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