Cargando…

Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory

Throughout the genome, nucleosomes often form regular arrays that differ in nucleosome repeat length (NRL), occupancy of linker histone H1 and transcriptional activity. Here, we report cryo-EM structures of human H1-containing tetranucleosome arrays with four physiologically relevant NRLs. The struc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dombrowski, Marco, Engeholm, Maik, Dienemann, Christian, Dodonova, Svetlana, Cramer, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113941/ https://www.ncbi.nlm.nih.gov/pubmed/35581345 http://dx.doi.org/10.1038/s41594-022-00768-w

Ejemplares similares

CTCF-dependent chromatin boundaries formed by asymmetric nucleosome arrays with decreased linker length
por: Clarkson, Christopher T, et al.
Publicado: (2019)

Structural basis of nucleosome transcription mediated by Chd1 and FACT
por: Farnung, Lucas, et al.
Publicado: (2021)

Linker DNA and histone contributions in nucleosome binding by p53
por: Nishimura, Masahiro, et al.
Publicado: (2020)

Binding of NF-κB to Nucleosomes: Effect of Translational Positioning, Nucleosome Remodeling and Linker Histone H1
por: Lone, Imtiaz Nisar, et al.
Publicado: (2013)

Pyrosequencing positions nucleosomes precisely
por: Owen-Hughes, Tom, et al.
Publicado: (2007)

Conformational selection and dynamic adaptation upon linker histone binding to the nucleosome
por: Öztürk, Mehmet Ali, et al.
Publicado: (2016)

On the structure and dynamics of the complex of the nucleosome and the linker histone
por: Pachov, Georgi V., et al.
Publicado: (2011)

Novel nucleosomal particles containing core histones and linker DNA but no histone H1
por: Cole, Hope A., et al.
Publicado: (2016)

Nucleosome–nucleosome interactions via histone tails and linker DNA regulate nuclear rigidity
por: Shimamoto, Yuta, et al.
Publicado: (2017)

Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding
por: Wang, Haibo, et al.
Publicado: (2019)

Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA
por: Hwang, William L., et al.
Publicado: (2014)

A quantitative investigation of linker histone interactions with nucleosomes and chromatin
por: White, Alison E., et al.
Publicado: (2016)

Docking data of selected human linker histone variants to the nucleosome
por: de Wit, Herna, et al.
Publicado: (2020)

The Linker Region of MacroH2A Promotes Self-association of Nucleosomal Arrays
por: Muthurajan, Uma M., et al.
Publicado: (2011)

Linker histone H1 and H3K56 acetylation are antagonistic regulators of nucleosome dynamics
por: Bernier, Morgan, et al.
Publicado: (2015)

Distinctive sequence patterns in metazoan and yeast nucleosomes: Implications for linker histone binding to AT-rich and methylated DNA
por: Cui, Feng, et al.
Publicado: (2009)

DNA and nucleosomes direct distinct folding of a linker histone H1 C-terminal domain
por: Fang, He, et al.
Publicado: (2012)

An All-Atom Model of the Chromatin Fiber Containing Linker Histones Reveals a Versatile Structure Tuned by the Nucleosomal Repeat Length
por: Wong, Hua, et al.
Publicado: (2007)

Nucleosomes can invade DNA territories occupied by their neighbors
por: Engeholm, Maik, et al.
Publicado: (2009)

Dynamic placement of the linker histone H1 associated with nucleosome arrangement and gene transcription in early Drosophila embryonic development
por: Hu, Jian, et al.
Publicado: (2018)

Accessibility of the histone H3 tail in the nucleosome for binding of paired readers
por: Gatchalian, Jovylyn, et al.
Publicado: (2017)

Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex
por: Dong, Shuqi, et al.
Publicado: (2023)

MeCP2 binds to nucleosome free (linker DNA) regions and to H3K9/H3K27 methylated nucleosomes in the brain
por: Thambirajah, Anita A., et al.
Publicado: (2012)

Comparative analysis of linker histone H1, MeCP2, and HMGD1 on nucleosome stability and target site accessibility
por: Riedmann, Caitlyn, et al.
Publicado: (2016)

Characterization of Dnmt1 Binding and DNA Methylation on Nucleosomes and Nucleosomal Arrays
por: Schrader, Anna, et al.
Publicado: (2015)

Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization
por: Choppakatla, Pavan, et al.
Publicado: (2021)

Correction to ‘MeCP2 binds to nucleosome free (linker DNA) regions and to H3K9/H3K27 methylated nucleosomes in the brain’
Publicado: (2022)

Identification of replication-dependent and replication-independent linker histone complexes: Tpr specifically promotes replication-dependent linker histone stability
por: Zhang, Pei, et al.
Publicado: (2016)

Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin
Publicado: (1979)

Linker Histone in Diseases
por: Ye, Xin, et al.
Publicado: (2017)

Loss of linker histone H1 in cellular senescence
por: Funayama, Ryo, et al.
Publicado: (2006)

Spatial heterogeneity of dynamics of H1 linker histone
por: Bernas, T., et al.
Publicado: (2014)

Promoter activity of the sea urchin (Paracentrotus lividus) nucleosomal H3 and H2A and linker H1 α-histone genes is modulated by enhancer and chromatin insulator
por: Cavalieri, Vincenzo, et al.
Publicado: (2009)

The Role of Histone H4 Biotinylation in the Structure of Nucleosomes
por: Filenko, Nina A., et al.
Publicado: (2011)

The interaction landscape between transcription factors and the nucleosome
por: Zhu, Fangjie, et al.
Publicado: (2018)

Binding of regulatory proteins to nucleosomes is modulated by dynamic histone tails
por: Peng, Yunhui, et al.
Publicado: (2021)

The basic linker of macroH2A stabilizes DNA at the entry/exit site of the nucleosome
por: Chakravarthy, Srinivas, et al.
Publicado: (2012)

The docking domain of histone H2A is required for H1 binding and RSC-mediated nucleosome remodeling
por: Shukla, Manu Shubhdarshan, et al.
Publicado: (2011)

Precise genome-wide mapping of single nucleosomes and linkers in vivo
por: Chereji, Răzvan V., et al.
Publicado: (2018)

Regulation of chromatin folding by conformational variations of nucleosome linker DNA
por: Buckwalter, Jenna M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_82iepp50jsruqrbbq2gtmom4ad