Characterization of two novel knock-in mouse models of syndromic retinal ciliopathy carrying hypomorphic Sdccag8 mutations

Mutations in serologically defined colon cancer autoantigen protein 8 (SDCCAG8) were first identified in retinal ciliopathy families a decade ago with unknown function. To investigate the pathogenesis of SDCCAG8-associated retinal ciliopathies in vivo, we employed CRISPR/Cas9-mediated homology-direc...

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Detalles Bibliográficos
Autores principales: Ren, Zhi-Lin, Zhang, Hou-Bin, Li, Lin, Yang, Zheng-Lin, Jiang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113982/
https://www.ncbi.nlm.nih.gov/pubmed/35503560
http://dx.doi.org/10.24272/j.issn.2095-8137.2021.387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113982/
https://www.ncbi.nlm.nih.gov/pubmed/35503560
http://dx.doi.org/10.24272/j.issn.2095-8137.2021.387

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