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BRG1 is a biomarker of hypertrophic cardiomyopathy in human heart specimens

Hypertrophic cardiomyopathy (HCM) is a genetic disease of the sarcomere that causes otherwise unexplained cardiac hypertrophy and is associated with sudden death. While previous studies showed the role of the epigenetic modifier Brg1 in mouse models of HCM, additional work is needed to identify its...

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Detalles Bibliográficos
Autores principales: Scherba, Jacob C., Halushka, Marc K., Andersen, Nicholas D., Maleszewski, Joseph J., Landstrom, Andrew P., Bursac, Nenad, Glass, Carolyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114001/
https://www.ncbi.nlm.nih.gov/pubmed/35581268
http://dx.doi.org/10.1038/s41598-022-11829-x