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Designing libraries for pooled CRISPR functional screens of long noncoding RNAs
Human and other genomes encode tens of thousands of long noncoding RNAs (lncRNAs), the vast majority of which remain uncharacterised. High-throughput functional screening methods, notably those based on pooled CRISPR-Cas perturbations, promise to unlock the biological significance and biomedical pot...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114037/ https://www.ncbi.nlm.nih.gov/pubmed/34533605 http://dx.doi.org/10.1007/s00335-021-09918-9 |