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Mice lacking growth-associated protein 43 develop cardiac remodeling and hypertrophy

Growth-associated protein 43 (GAP43) is found in skeletal muscle, localized near the calcium release units. In interaction with calmodulin (CaM), it indirectly modulates the activity of dihydropyridine and ryanodine Ca(2+) channels. GAP43–CaM interaction plays a key role in intracellular Ca(2+) home...

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Detalles Bibliográficos
Autores principales: Bevere, Michele, Morabito, Caterina, Guarnieri, Simone, Mariggiò, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114049/
https://www.ncbi.nlm.nih.gov/pubmed/35201398
http://dx.doi.org/10.1007/s00418-022-02089-x