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RORA alleviates LPS-induced apoptosis of renal epithelial cells by promoting PGC-1α transcription
OBJECTIVE: To explore the effect of RORA on LPS-induced renal epithelial cell apoptosis and the underlying mechanism. METHODS: LPS-treated HK-2 cells were established as a cellular model of acute kidney injury. The expression of RORA or/and PGC-1α in LPS-induced HK-2 cells was altered by transfectio...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114077/ https://www.ncbi.nlm.nih.gov/pubmed/35195816 http://dx.doi.org/10.1007/s10157-022-02184-2 |