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RORA alleviates LPS-induced apoptosis of renal epithelial cells by promoting PGC-1α transcription

OBJECTIVE: To explore the effect of RORA on LPS-induced renal epithelial cell apoptosis and the underlying mechanism. METHODS: LPS-treated HK-2 cells were established as a cellular model of acute kidney injury. The expression of RORA or/and PGC-1α in LPS-induced HK-2 cells was altered by transfectio...

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Detalles Bibliográficos
Autores principales: Li, Dayong, Liu, Guanlan, Wu, Yundou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114077/
https://www.ncbi.nlm.nih.gov/pubmed/35195816
http://dx.doi.org/10.1007/s10157-022-02184-2