Cargando…

RORA alleviates LPS-induced apoptosis of renal epithelial cells by promoting PGC-1α transcription

OBJECTIVE: To explore the effect of RORA on LPS-induced renal epithelial cell apoptosis and the underlying mechanism. METHODS: LPS-treated HK-2 cells were established as a cellular model of acute kidney injury. The expression of RORA or/and PGC-1α in LPS-induced HK-2 cells was altered by transfectio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Dayong, Liu, Guanlan, Wu, Yundou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Nature Singapore 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114077/ https://www.ncbi.nlm.nih.gov/pubmed/35195816 http://dx.doi.org/10.1007/s10157-022-02184-2

Ejemplares similares

Circ_0066881 targets miR-144-5p/RORA axis to alleviate LPS-induced apoptotic and inflammatory damages in human periodontal ligament cells
por: Li, Qin, et al.
Publicado: (2022)

Skeletal Muscle PGC-1α Is Required for Maintaining an Acute LPS-Induced TNFα Response
por: Olesen, Jesper, et al.
Publicado: (2012)

Chlorogenic Acid Alleviates LPS-Induced Inflammation and Oxidative Stress by Modulating CD36/AMPK/PGC-1α in RAW264.7 Macrophages
por: Gu, Tiantian, et al.
Publicado: (2023)

RORA and Autism in The Isfahan Population: Is There An Epigenetic Relationship
por: Salehi, Mansoor, et al.
Publicado: (2017)

Rora Regulates Neutrophil Migration and Activation in Zebrafish
por: Hsu, Alan Y., et al.
Publicado: (2022)

Knockdown of 11β-hydroxysteroid dehydrogenase type 1 alleviates LPS-induced myocardial dysfunction through the AMPK/SIRT1/PGC-1α pathway
por: Zhu, Dongmei, et al.
Publicado: (2023)

Exploring the Effect of Dapagliflozin on Alcoholic Kidney Injury and Renal Interstitial Fibrosis in Rats Based on TIMP-1/MMP-24 Pathway
por: Wu, Yundou, et al.
Publicado: (2021)

Morroniside Promotes PGC-1α-Mediated Cholesterol Efflux in Sodium Palmitate or High Glucose-Induced Mouse Renal Tubular Epithelial Cells
por: Gao, Junwei, et al.
Publicado: (2021)

Sirt6 opposes glycochenodeoxycholate-induced apoptosis of biliary epithelial cells through the AMPK/PGC-1α pathway
por: Li, Jiye, et al.
Publicado: (2020)

Role of simvastatin and RORa activity in the macrophage apoptotic pathway
por: Çoban, Neslihan, et al.
Publicado: (2017)

Exercise-induced PGC-1α transcriptional factors in skeletal muscle
por: Jung, Suryun, et al.
Publicado: (2014)

Anti-TWEAK Antibody Alleviates Renal Interstitial Fibrosis by Increasing PGC-1α Expression in Lupus Nephritis
por: Xue, Leixi, et al.
Publicado: (2021)

ZLN005 Alleviates In Vivo and In Vitro Renal Fibrosis via PGC-1α-Mediated Mitochondrial Homeostasis
por: Zhu, Pengfei, et al.
Publicado: (2022)

Proanthocyanidin Alleviates Liver Ischemia/Reperfusion Injury by Suppressing Autophagy and Apoptosis via the PPARα/PGC1α Signaling Pathway
por: Yao, Zhilu, et al.
Publicado: (2023)

A map of the PGC-1α- and NT-PGC-1α-regulated transcriptional network in brown adipose tissue
por: Chang, Ji Suk, et al.
Publicado: (2018)

PGC1α Loss Promotes Lung Cancer Metastasis through Epithelial-Mesenchymal Transition
por: Oh, Taek-In, et al.
Publicado: (2021)

PGC-1α Is Indispensable in Purple Potato Promoted Intestinal Epithelial Differentiation and Mitochondrial Biogenesis
por: Sun, Qi, et al.
Publicado: (2022)

Mapping Rora expression in resting and activated CD4+ T cells
por: Haim-Vilmovsky, Liora, et al.
Publicado: (2021)

Transcriptional Activity of PGC-1α and NT-PGC-1α Is Differentially Regulated by Twist-1 in Brown Fat Metabolism
por: Jun, Hee-Jin, et al.
Publicado: (2012)

Regulation of Mitochondrial Proliferation by PGC-1α Induces Cellular Apoptosis in Musculoskeletal Malignancies
por: Onishi, Yasuo, et al.
Publicado: (2014)

ROCK2 knockdown alleviates LPS-induced inflammatory injury and apoptosis of renal tubular epithelial cells via the NF-κB/NLRP3 signaling pathway
por: Qian, Xinfeng, et al.
Publicado: (2022)

PGC−1α Promoter Methylation in Parkinson’s Disease
por: Su, Xiaomin, et al.
Publicado: (2015)

CRTC2 enhances HBV transcription and replication by inducing PGC1α expression
por: Tian, Xiaohui, et al.
Publicado: (2014)

Aldehyde dehydrogenase 2 alleviates mitochondrial dysfunction by promoting PGC-1α-mediated biogenesis in acute kidney injury
por: Li, Jiaying, et al.
Publicado: (2023)

Astragaloside IV ameliorates peritoneal fibrosis by promoting PGC‐1α to reduce apoptosis in vitro and in vivo
por: Xie, Mingxia, et al.
Publicado: (2023)

PGC-1α regulates airway epithelial barrier dysfunction induced by house dust mite
por: Saito, Tsutomu, et al.
Publicado: (2021)

PGC‐1α promotes exercise‐induced autophagy in mouse skeletal muscle
por: Halling, Jens F., et al.
Publicado: (2016)

Regulation of P-Glycoprotein in Renal Proximal Tubule Epithelial Cells by LPS and TNF-α
por: Heemskerk, Suzanne, et al.
Publicado: (2010)

Adipocyte-Specific Expression of PGC1α Promotes Adipocyte Browning and Alleviates Obesity-Induced Metabolic Dysfunction in an HO-1-Dependent Fashion
por: Shen, Shin-Hsueh, et al.
Publicado: (2022)

Transcriptional coactivator NT‐PGC‐1α promotes gluconeogenic gene expression and enhances hepatic gluconeogenesis
por: Chang, Ji Suk, et al.
Publicado: (2016)

Glucose Restriction Promotes Osteocyte Specification by Activating a PGC-1α-Dependent Transcriptional Program
por: Sánchez-de-Diego, Cristina, et al.
Publicado: (2019)

Genome-wide identification of transcriptional targets of RORA reveals direct regulation of multiple genes associated with autism spectrum disorder
por: Sarachana, Tewarit, et al.
Publicado: (2013)

Investigation of sex differences in the expression of RORA and its transcriptional targets in the brain as a potential contributor to the sex bias in autism
por: Hu, Valerie W, et al.
Publicado: (2015)

Correction to: PGC-1α regulates airway epithelial barrier dysfunction induced by house dust mite
por: Saito, Tsutomu, et al.
Publicado: (2021)

PGC-1α alleviates mitochondrial dysfunction via TFEB-mediated autophagy in cisplatin-induced acute kidney injury
por: Yuan, Longhui, et al.
Publicado: (2021)

Epigenetic Modifications of the PGC-1α Promoter during Exercise Induced Expression in Mice
por: Lochmann, Timothy L., et al.
Publicado: (2015)

Loss of PGC-1α in RPE induces mesenchymal transition and promotes retinal degeneration
por: Rosales, Mariana Aparecida Brunini, et al.
Publicado: (2019)

Geraniol alleviates LPS-induced acute lung injury in mice via inhibiting inflammation and apoptosis
por: Jiang, Kangfeng, et al.
Publicado: (2017)

Dulaglutide Alleviates LPS-Induced Injury in Cardiomyocytes
por: Wang, Rijun, et al.
Publicado: (2021)

LPS promotes resistance to TRAIL-induced apoptosis in pancreatic cancer
por: Beyer, Katharina, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_8qe7ltnqvugb9r4ketog7av12q