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METTL3-mediated m(6)A RNA methylation regulates dorsal lingual epithelium homeostasis

The dorsal lingual epithelium, which is composed of taste buds and keratinocytes differentiated from K14(+) basal cells, discriminates taste compounds and maintains the epithelial barrier. N6-methyladenosine (m(6)A) is the most abundant mRNA modification in eukaryotic cells. How METTL3-mediated m(6)...

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Detalles Bibliográficos
Autores principales: Xiong, Qiuchan, Liu, Caojie, Zheng, Xin, Zhou, Xinyi, Lei, Kexin, Zhang, Xiaohan, Wang, Qian, Lin, Weimin, Tong, Ruizhan, Xu, Ruoshi, Yuan, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114113/
https://www.ncbi.nlm.nih.gov/pubmed/35581183
http://dx.doi.org/10.1038/s41368-022-00176-2