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A novel ATG5 interaction with Ku70 potentiates DNA repair upon genotoxic stress

The maintenance of cellular homeostasis in living organisms requires a balance between anabolic and catabolic reactions. Macroautophagy (autophagy herein) is determined as one of the major catabolic reactions. Autophagy is an evolutionarily conserved stress response pathway that is activated by vari...

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Detalles Bibliográficos
Autores principales: Demirbag-Sarikaya, Sinem, Akkoc, Yunus, Turgut, Sıla, Erbil-Bilir, Secil, Kocaturk, Nur Mehpare, Dengjel, Joern, Gozuacik, Devrim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114114/
https://www.ncbi.nlm.nih.gov/pubmed/35581289
http://dx.doi.org/10.1038/s41598-022-11704-9