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Neutrophil elastase aggravates periodontitis by disrupting gingival epithelial barrier via cleaving cell adhesion molecules

Neutrophil elastase (NE) functions as a host defense factor; however, excessive NE activity can potentially destroy human tissues. Although NE activity is positively correlated to gingival crevicular fluid and clinical attachment loss in periodontitis, the underlying mechanisms by which NE aggravate...

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Detalles Bibliográficos
Autores principales: Hiyoshi, Takumi, Domon, Hisanori, Maekawa, Tomoki, Tamura, Hikaru, Isono, Toshihito, Hirayama, Satoru, Sasagawa, Karin, Takizawa, Fumio, Tabeta, Koichi, Terao, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114116/
https://www.ncbi.nlm.nih.gov/pubmed/35581391
http://dx.doi.org/10.1038/s41598-022-12358-3