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A TEMPOL and rapamycin loaded nanofiber-covered stent favors endothelialization and mitigates neointimal hyperplasia and local inflammation

An increased level of reactive oxygen species (ROS) plays a major role in endothelial dysfunction and vascular smooth muscle cell (VSMC) proliferation during in-stent thrombosis and restenosis after coronary artery stenting. Herein, we report an electrospun core-shell nanofiber coloaded with 4-hydro...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Lu, Jian, Yin, Jiasheng, Chen, Han, Liu, Hongmei, Xu, Fei, Zang, Tongtong, Xu, Rende, Li, Chenguang, Wu, Yizhe, Wu, Qilin, Fei, Xiang, Zhu, Meifang, Shen, Li, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114161/
https://www.ncbi.nlm.nih.gov/pubmed/35600979
http://dx.doi.org/10.1016/j.bioactmat.2022.04.033