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A murine model of large-scale bone regeneration reveals a selective requirement for Sonic Hedgehog

Building and maintaining skeletal tissue requires the activity of skeletal stem and progenitor cells (SSPCs). Following injury, local pools of these SSPCs become active and coordinate to build new cartilage and bone tissues. While recent studies have identified specific markers for these SSPCs, how...

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Detalles Bibliográficos
Autores principales: Serowoky, Maxwell A., Kuwahara, Stephanie T., Liu, Shuwan, Vakhshori, Venus, Lieberman, Jay R., Mariani, Francesca V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114339/
https://www.ncbi.nlm.nih.gov/pubmed/35581202
http://dx.doi.org/10.1038/s41536-022-00225-8