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Spatiotemporal stop-and-go dynamics of the mitochondrial TOM core complex correlates with channel activity

Single-molecule studies can reveal phenomena that remain hidden in ensemble measurements. Here we show the correlation between lateral protein diffusion and channel activity of the general protein import pore of mitochondria (TOM-CC) in membranes resting on ultrathin hydrogel films. Using electrode-...

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Detalles Bibliográficos
Autores principales: Wang, Shuo, Findeisen, Lukas, Leptihn, Sebastian, Wallace, Mark I., Hörning, Marcel, Nussberger, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114391/
https://www.ncbi.nlm.nih.gov/pubmed/35581327
http://dx.doi.org/10.1038/s42003-022-03419-4