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Immunotherapeutic Effects of Different Doses of Mycobacterium tuberculosis ag85a/b DNA Vaccine Delivered by Electroporation

BACKGROUND: Tuberculosis (TB) is a major global public health problem. New treatment methods on TB are urgently demanded. METHODS: Ninety-six female BALB/c mice were challenged with 2×10(4) colony-forming units (CFUs) of MTB H(37)Rv through tail vein injection, then was treated with 10μg, 50μg, 100μ...

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Detalles Bibliográficos
Autores principales: Liang, Yan, Cui, Lei, Xiao, Li, Liu, Xiao, Yang, Yourong, Ling, Yanbo, Wang, Tong, Wang, Lan, Wang, Jie, Wu, Xueqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114437/
https://www.ncbi.nlm.nih.gov/pubmed/35603155
http://dx.doi.org/10.3389/fimmu.2022.876579