Critical roles of FGF, RA, and WNT signalling in the development of the human otic placode and subsequent lineages in a dish

INTRODUCTION: Efficient induction of the otic placode, the developmental origin of the inner ear from human pluripotent stem cells (hPSCs), provides a robust platform for otic development and sensorineural hearing loss modelling. Nevertheless, there remains a limited capacity of otic lineage specifi...

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Detalles Bibliográficos
Autores principales: Saeki, Tsubasa, Yoshimatsu, Sho, Ishikawa, Mitsuru, Hon, Chung-Chau, Koya, Ikuko, Shibata, Shinsuke, Hosoya, Makoto, Saegusa, Chika, Ogawa, Kaoru, Shin, Jay W., Fujioka, Masato, Okano, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114627/
https://www.ncbi.nlm.nih.gov/pubmed/35620640
http://dx.doi.org/10.1016/j.reth.2022.04.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114627/
https://www.ncbi.nlm.nih.gov/pubmed/35620640
http://dx.doi.org/10.1016/j.reth.2022.04.008

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