The Role of Mechanically-Activated Ion Channels Piezo1, Piezo2, and TRPV4 in Chondrocyte Mechanotransduction and Mechano-Therapeutics for Osteoarthritis

Mechanical factors play critical roles in the pathogenesis of joint disorders like osteoarthritis (OA), a prevalent progressive degenerative joint disease that causes debilitating pain. Chondrocytes in the cartilage are responsible for extracellular matrix (ECM) turnover, and mechanical stimuli heav...

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Detalles Bibliográficos
Autores principales: Gao, Winni, Hasan, Hamza, Anderson, Devon E., Lee, Whasil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114637/
https://www.ncbi.nlm.nih.gov/pubmed/35602590
http://dx.doi.org/10.3389/fcell.2022.885224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114637/
https://www.ncbi.nlm.nih.gov/pubmed/35602590
http://dx.doi.org/10.3389/fcell.2022.885224

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