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Differences in the expression of DNA methyltransferases and demethylases in leukocytes and the severity of pulmonary arterial hypertension between ethnic groups

The loss of ten‐eleven translocation (TET2) methylcytosine dioxygenase expression contributes to the pathobiology of pulmonary arterial hypertension (PAH). However, whether the expression and activity of other TETs and DNA methyltransferases (DNMTs) are altered in PAH remains enigmatic. Therefore, o...

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Detalles Bibliográficos
Autores principales: D’Addario, Catherine A., Lanier, Gregg M., Jacob, Christina, Bauer, Natalie, Hewes, Jenny L., Bhadra, Aritra, Gupte, Sachin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114656/
https://www.ncbi.nlm.nih.gov/pubmed/35581740
http://dx.doi.org/10.14814/phy2.15282