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Single-Cell Transcriptomics Uncovers Cellular Heterogeneity, Mechanisms, and Therapeutic Targets for Parkinson’s Disease

Objective: This study aimed to exploit cellular heterogeneity for revealing mechanisms and identifying therapeutic targets for Parkinson’s disease (PD) via single-cell transcriptomics. Methods: Single-cell RNA sequencing (scRNA-seq) data on midbrain specimens from PD and healthy individuals were obt...

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Detalles Bibliográficos
Autores principales: Huang, Jianjun, Liu, Li, Qin, Lingling, Huang, Hehua, Li, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114673/
https://www.ncbi.nlm.nih.gov/pubmed/35601482
http://dx.doi.org/10.3389/fgene.2022.686739