Complementary protocols to evaluate inhibitors against the DnaK chaperone network

Bacterial DnaK belongs to the Hsp70 chaperone family, which plays a critical role in maintaining proteostasis by catalyzing protein folding, and is a proposed antibacterial target in the pathogen Mycobacterium tuberculosis. Here, we describe an experimental toolbox for evaluating inhibitors against...

Descripción completa

Detalles Bibliográficos
Autores principales: Richards, Aweon, Yawson, Gideon K., Nelson, Brock, Lupoli, Tania J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114682/
https://www.ncbi.nlm.nih.gov/pubmed/35600924
http://dx.doi.org/10.1016/j.xpro.2022.101381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114682/
https://www.ncbi.nlm.nih.gov/pubmed/35600924
http://dx.doi.org/10.1016/j.xpro.2022.101381

Ejemplares similares