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T Cell Specific BOB.1/OBF.1 Expression Promotes Germinal Center Response and T Helper Cell Differentiation

The transcriptional co-activator BOB.1/OBF.1 is expressed in both B and T cells. The main characteristic of conventional BOB.1/OBF.1 deficient mice is the complete absence of germinal centers (GCs). This defect was mainly attributed to the defective B cell compartment. However, it is unknown whether...

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Detalles Bibliográficos
Autores principales: Betzler, Annika C., Ezić, Jasmin, Abou Kors, Tsima, Hoffmann, Thomas K., Wirth, Thomas, Brunner, Cornelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114770/
https://www.ncbi.nlm.nih.gov/pubmed/35603192
http://dx.doi.org/10.3389/fimmu.2022.889564