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Screening for Anti-HMGCR Antibodies in a Large Single Myositis Center Reveals Infrequent Exposure to Statins and Diversiform Presentation of the Disease

BACKGROUND: The objective of this study is to assess the frequency of autoantibodies against 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR) in a single center myositis cohort and to analyze associations with statin exposure, clinical features, and outcome of disease course. METHODS: A tota...

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Detalles Bibliográficos
Autores principales: Szczesny, Piotr, Barsotti, Simone, Nennesmo, Inger, Danielsson, Olof, Dastmalchi, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114810/
https://www.ncbi.nlm.nih.gov/pubmed/35603214
http://dx.doi.org/10.3389/fimmu.2022.866701