Mitoribosomal defects aggravate liver cancer via aberrant glycolytic flux and T cell exhaustion

BACKGROUND: Mitochondria are involved in cancer energy metabolism, although the mechanisms underlying the involvement of mitoribosomal dysfunction in hepatocellular carcinoma (HCC) remain poorly understood. Here, we investigated the effects of mitoribosomal impairment-mediated alterations on the imm...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Byong-Sop, Moon, Ji Sun, Tian, Jingwen, Lee, Ho Yeop, Sim, Byeong Chang, Kim, Seok-Hwan, Kang, Seul Gi, Kim, Jung Tae, Nga, Ha Thi, Benfeitas, Rui, Kim, Yeongmin, Park, Sanghee, Wolfe, Robert R., Eun, Hyuk Soo, Shong, Minho, Lee, Sunjae, Kim, Il-Young, Yi, Hyon-Seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114962/
https://www.ncbi.nlm.nih.gov/pubmed/35580931
http://dx.doi.org/10.1136/jitc-2021-004337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114962/
https://www.ncbi.nlm.nih.gov/pubmed/35580931
http://dx.doi.org/10.1136/jitc-2021-004337

Ejemplares similares