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Scopoletin protects retinal ganglion cells 5 from high glucose-induced injury in a cellular model of diabetic retinopathy via ROS-dependent p38 and JNK signaling cascade

The protective activity of scopoletin (SPT) against glucose-induced cataract has been attributed to attenuation of aldose reductase activity and oxidative stress in a rat model. The present investigation was aimed to study the protective effect and mechanism of SPT in retinal ganglia cells (RGC) und...

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Detalles Bibliográficos
Autores principales: Pan, Jinxin, Liu, Haojie, Wu, Qi, Zhou, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115602/
https://www.ncbi.nlm.nih.gov/pubmed/35600154
http://dx.doi.org/10.5114/ceji.2022.115710