A facile metal-free one-flask synthesis of multi-substituted furans via a BF(3)·Et(2)O mediated formal [4 + 1] reaction of 3-chloro-3-phenyldiazirines and α,β-alkenyl ketones

A facile, efficient and metal free one-flask approach to diversely substituted furans from easily accessible 3-chloro-3-phenyldiazirines and α,β-alkenyl ketones is reported. This protocol integrates three steps of cyclopropanation, Cloke–Wilson rearrangement and elimination of HCl in one-flask to gi...

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Detalles Bibliográficos
Autores principales: Zhang, Zixin, Huang, Aimin, Ma, Lin, Xu, Jian-hua, Zhang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115646/
https://www.ncbi.nlm.nih.gov/pubmed/35702439
http://dx.doi.org/10.1039/d2ra01472f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115646/
https://www.ncbi.nlm.nih.gov/pubmed/35702439
http://dx.doi.org/10.1039/d2ra01472f

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