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Metal‐HisTag coordination for remote loading of very small quantities of biomacromolecules into PLGA microspheres

Challenges to discovery and preclinical development of long‐acting release systems for protein therapeutics include protein instability, use of organic solvents during encapsulation, specialized equipment and personnel, and high costs of proteins. We sought to overcome these issues by combining remo...

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Detalles Bibliográficos
Autores principales: Albert, Jason, Chang, Rae Sung, Garcia, George A., Schwendeman, Steven P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115689/
https://www.ncbi.nlm.nih.gov/pubmed/35600641
http://dx.doi.org/10.1002/btm2.10272