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Macrophage‐targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by the infiltration of macrophages in the fibrotic region. Currently, no therapeutic strategies effectively control disease progression, and the 5‐year mortality of patients after diagnosis is unacceptably h...

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Detalles Bibliográficos
Autores principales: Mou, Yong, Wu, Guo‐Rao, Wang, Qi, Pan, Ting, Zhang, Lei, Xu, Yongjian, Xiong, Weining, Zhou, Qing, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115697/
https://www.ncbi.nlm.nih.gov/pubmed/35600643
http://dx.doi.org/10.1002/btm2.10280