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Long term therapeutic effects of icariin‐loaded PLGA microspheres in an experimental model of optic nerve ischemia via modulation of CEBP‐β/G‐CSF/noncanonical NF‐κB axis

An ischemic insult at optic nerve (ON) is followed by detrimental neuroinflammation that results in progressive and long‐lasting retinal ganglion cell (RGC) death and vision loss. Icariin was reported to be a safe and effective natural anti‐inflammatory drug. Herein, we evaluated the long‐term thera...

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Detalles Bibliográficos
Autores principales: Desai, Tushar Dnyaneshwar, Wen, Yao‐Tseng, Daddam, Jayasimha Rayalu, Cheng, Felice, Chen, Chia‐Ching, Pan, Chien‐Lin, Lin, Keh‐Liang, Tsai, Rong‐Kung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115698/
https://www.ncbi.nlm.nih.gov/pubmed/35600664
http://dx.doi.org/10.1002/btm2.10289