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Long term therapeutic effects of icariin‐loaded PLGA microspheres in an experimental model of optic nerve ischemia via modulation of CEBP‐β/G‐CSF/noncanonical NF‐κB axis
An ischemic insult at optic nerve (ON) is followed by detrimental neuroinflammation that results in progressive and long‐lasting retinal ganglion cell (RGC) death and vision loss. Icariin was reported to be a safe and effective natural anti‐inflammatory drug. Herein, we evaluated the long‐term thera...
Autores principales: | Desai, Tushar Dnyaneshwar, Wen, Yao‐Tseng, Daddam, Jayasimha Rayalu, Cheng, Felice, Chen, Chia‐Ching, Pan, Chien‐Lin, Lin, Keh‐Liang, Tsai, Rong‐Kung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115698/ https://www.ncbi.nlm.nih.gov/pubmed/35600664 http://dx.doi.org/10.1002/btm2.10289 |
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