Engineering a switchable single‐chain TEV protease to control protein maturation in living neurons

Engineered proteases are promising tools to address physiological and pathophysiological questions as well as to develop new therapeutic approaches. Here we introduce a new genetically encoded engineered single‐chain tobacco etch virus protease, allowing to control proprotein cleavage in different c...

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Detalles Bibliográficos
Autores principales: Renna, Pietro, Ripoli, Cristian, Dagliyan, Onur, Pastore, Francesco, Rinaudo, Marco, Re, Agnese, Paciello, Fabiola, Grassi, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115699/
https://www.ncbi.nlm.nih.gov/pubmed/35600650
http://dx.doi.org/10.1002/btm2.10292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115699/
https://www.ncbi.nlm.nih.gov/pubmed/35600650
http://dx.doi.org/10.1002/btm2.10292

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