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TIMP‐1‐expressing breast tumor spheroids for the evaluation of drug penetration and efficacy

Abundance of stromal cells and extracellular matrix (ECM) is observed in breast cancer, acting as a barrier for drug penetration and presenting a key issue for developing efficient therapeutics. In this study, we aimed to develop a three‐dimensional (3D) multicellular tumor model comprising cancer a...

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Detalles Bibliográficos
Autores principales: Bae, In Yeong, Choi, Wooshik, Oh, Seung Ja, Kim, Chansoo, Kim, Sang‐Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115709/
https://www.ncbi.nlm.nih.gov/pubmed/35600659
http://dx.doi.org/10.1002/btm2.10286