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Ruthenium-catalyzed asymmetric hydrogenation of aromatic and heteroaromatic ketones using cinchona alkaloid-derived NNP ligands

A series of cinchona alkaloid-based NNP ligands, including a new one, have been employed for the asymmetric hydrogenation of ketones. By combining ruthenium complexes, various aromatic and heteroaromatic ketones were smoothly reacted, yielding valuable chiral alcohols with extremely high 99.9% ee. M...

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Detalles Bibliográficos
Autores principales: Zhang, Ling, Chen, Qian, Li, Linlin, Jiang, Jian, Sun, Hao, Li, Li, Liu, Ting, Zhang, Lin, Li, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115770/
https://www.ncbi.nlm.nih.gov/pubmed/35702223
http://dx.doi.org/10.1039/d2ra02211g