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Ruthenium-catalyzed asymmetric hydrogenation of aromatic and heteroaromatic ketones using cinchona alkaloid-derived NNP ligands
A series of cinchona alkaloid-based NNP ligands, including a new one, have been employed for the asymmetric hydrogenation of ketones. By combining ruthenium complexes, various aromatic and heteroaromatic ketones were smoothly reacted, yielding valuable chiral alcohols with extremely high 99.9% ee. M...
Autores principales: | Zhang, Ling, Chen, Qian, Li, Linlin, Jiang, Jian, Sun, Hao, Li, Li, Liu, Ting, Zhang, Lin, Li, Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115770/ https://www.ncbi.nlm.nih.gov/pubmed/35702223 http://dx.doi.org/10.1039/d2ra02211g |
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