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FOXO Dictates Initiation of B Cell Development and Myeloid Restriction in Common Lymphoid Progenitors
The development of B cells relies on an intricate network of transcription factors critical for developmental progression and lineage commitment. In the B cell developmental trajectory, a temporal switch from predominant Foxo3 to Foxo1 expression occurs at the CLP stage. Utilizing VAV-iCre mediated...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116193/ https://www.ncbi.nlm.nih.gov/pubmed/35603175 http://dx.doi.org/10.3389/fimmu.2022.880668 |