Systematic optimization of host-directed therapeutic targets and preclinical validation of repositioned antiviral drugs

Inhibition of host protein functions using established drugs produces a promising antiviral effect with excellent safety profiles, decreased incidence of resistant variants and favorable balance of costs and risks. Genomic methods have produced a large number of robust host factors, providing candid...

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Detalles Bibliográficos
Autores principales: Xie, Dafei, He, Song, Han, Lu, Wu, Lianlian, Huang, Hai, Tao, Huan, Zhou, Pingkun, Shi, Xunlong, Bai, Hui, Bo, Xiaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Problem Solving Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116211/
https://www.ncbi.nlm.nih.gov/pubmed/35238349
http://dx.doi.org/10.1093/bib/bbac047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116211/
https://www.ncbi.nlm.nih.gov/pubmed/35238349
http://dx.doi.org/10.1093/bib/bbac047

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