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Systematic optimization of host-directed therapeutic targets and preclinical validation of repositioned antiviral drugs
Inhibition of host protein functions using established drugs produces a promising antiviral effect with excellent safety profiles, decreased incidence of resistant variants and favorable balance of costs and risks. Genomic methods have produced a large number of robust host factors, providing candid...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116211/ https://www.ncbi.nlm.nih.gov/pubmed/35238349 http://dx.doi.org/10.1093/bib/bbac047 |