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Evaluating performance of existing computational models in predicting CD8+ T cell pathogenic epitopes and cancer neoantigens

T cell recognition of a cognate peptide–major histocompatibility complex (pMHC) presented on the surface of infected or malignant cells is of the utmost importance for mediating robust and long-term immune responses. Accurate predictions of cognate pMHC targets for T cell receptors would greatly fac...

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Detalles Bibliográficos
Autores principales: Buckley, Paul R, Lee, Chloe H, Ma, Ruichong, Woodhouse, Isaac, Woo, Jeongmin, Tsvetkov, Vasily O, Shcherbinin, Dmitrii S, Antanaviciute, Agne, Shughay, Mikhail, Rei, Margarida, Simmons, Alison, Koohy, Hashem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116217/
https://www.ncbi.nlm.nih.gov/pubmed/35471658
http://dx.doi.org/10.1093/bib/bbac141