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Red ginseng polysaccharide exhibits anticancer activity through GPX4 downregulation-induced ferroptosis

CONTEXT: Red ginseng polysaccharide (RGP) is an active component of the widely used medicinal plant Panax ginseng C. A. Meyer (Araliaceae), which has displayed promising activities against cancer cells. However, the detailed molecular mechanism of RGP in ferroptosis is still unknown. OBJECTIVE: This...

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Detalles Bibliográficos
Autores principales: Zhai, Feng-guo, Liang, Qi-chao, Wu, Yi-yan, Liu, Jia-qi, Liu, Jia-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116236/
https://www.ncbi.nlm.nih.gov/pubmed/35575436
http://dx.doi.org/10.1080/13880209.2022.2066139