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Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins

α-synuclein, β-synuclein, and γ-synuclein are abundantly expressed proteins in the vertebrate nervous system. α-synuclein functions in neurotransmitter release by binding to and clustering synaptic vesicles and chaperoning SNARE-complex assembly. Pathologically, aggregates originating from soluble p...

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Detalles Bibliográficos
Autores principales: Carnazza, Kathryn E., Komer, Lauren E., Xie, Ying Xue, Pineda, André, Briano, Juan Antonio, Gao, Virginia, Na, Yoonmi, Ramlall, Trudy, Buchman, Vladimir L., Eliezer, David, Sharma, Manu, Burré, Jacqueline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116446/
https://www.ncbi.nlm.nih.gov/pubmed/35417693
http://dx.doi.org/10.1016/j.celrep.2022.110675