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Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins
α-synuclein, β-synuclein, and γ-synuclein are abundantly expressed proteins in the vertebrate nervous system. α-synuclein functions in neurotransmitter release by binding to and clustering synaptic vesicles and chaperoning SNARE-complex assembly. Pathologically, aggregates originating from soluble p...
Autores principales: | Carnazza, Kathryn E., Komer, Lauren E., Xie, Ying Xue, Pineda, André, Briano, Juan Antonio, Gao, Virginia, Na, Yoonmi, Ramlall, Trudy, Buchman, Vladimir L., Eliezer, David, Sharma, Manu, Burré, Jacqueline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116446/ https://www.ncbi.nlm.nih.gov/pubmed/35417693 http://dx.doi.org/10.1016/j.celrep.2022.110675 |
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