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Population Pharmacokinetics of Caspofungin and Dose Simulations in Heart Transplant Recipients

The effect of heart transplantation (HTx) on the pharmacokinetics (PK) of caspofungin is not well-characterized. The aim of this study was to investigate the population PK of caspofungin in HTx and non-HTx patients and to identify covariates that may affect the PK of caspofungin. Seven successive bl...

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Detalles Bibliográficos
Autores principales: Wu, Zheng, Lan, Jinhua, Wang, Xipei, Wu, Yijin, Yao, Fen, Wang, Yifan, Zhao, Bo-xin, Wang, Yirong, Chen, Jingchun, Chen, Chunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116478/
https://www.ncbi.nlm.nih.gov/pubmed/35389237
http://dx.doi.org/10.1128/aac.02249-21